{"id":3477,"date":"2018-07-09T12:25:41","date_gmt":"2018-07-09T12:25:41","guid":{"rendered":"https:\/\/cnls.sn\/?post_type=nos_actualites&p=3477"},"modified":"2018-07-09T12:25:41","modified_gmt":"2018-07-09T12:25:41","slug":"recherche-et-vih-un-nouveau-vaccin-prometteur-teste-prochainement","status":"publish","type":"post","link":"https:\/\/cnls.sn\/?p=3477","title":{"rendered":"Recherche et Vih :Un nouveau vaccin prometteur test\u00e9 prochainement"},"content":{"rendered":"

Les r\u00e9sultats d<\/span>\u2019un<\/span> vaccin exp\u00e9rimental<\/span> contre le sida viennent d\u2019\u00eatre pr\u00e9sent\u00e9s par l\u2019\u00e9quipe du virologue Dan Barouch de l\u2019universit\u00e9 d\u2019Harvard (\u00c9tats-Unis). Un<\/span> test sur des milliers de personnes va \u00eatre lanc\u00e9 en Afrique australe.<\/span><\/p>\n

Des chercheurs ont fait \u00e9tat samedi\u00a0 07 Juillet 2018,d<\/span>\u2019un progr\u00e8s encourageant, avec un vaccin exp\u00e9rimental qui a provoqu\u00e9 une r\u00e9action immunitaire chez des humains<\/span> et prot\u00e9g\u00e9 des macaques de l\u2019infection.<\/span><\/p>\n

Le d\u00e9veloppement de ce potentiel<\/span> vaccin, s\u00fbr pour l\u2019homme, est maintenant suffisamment avanc\u00e9 pour lancer un test sur 2\u2009600 femmes en Afrique australe<\/a>.<\/span><\/p>\n

\u00ab\u2009Ces r\u00e9sultats repr\u00e9sentent une \u00e9tape importante\u2009\u00bb<\/strong>, a soulign\u00e9 le<\/span> directeur de l\u2019\u00e9tude, le virologue Dan Barouch, dans un communiqu\u00e9 de la revue The Lancet<\/span>. Rejoint par d\u2019autres experts, il a cependant pr\u00e9venu qu\u2019il n\u2019y avait aucune garantie que les tests suivants soient aussi positifs. \u00ab\u2009Nous devons rester prudents\u2009\u00bb<\/strong>, a-t-il d\u00e9clar\u00e9.*<\/span><\/p>\n

Deux tiers des macaques prot\u00e9g\u00e9s par le vaccin<\/strong><\/span><\/p>\n

Deux tiers des macaques rh\u00e9sus ont \u00e9t\u00e9 prot\u00e9g\u00e9s par le vaccin<\/span> dans les tests de laboratoire.Les r\u00e9sultats du test grandeur nature, appel\u00e9 Imbokodo (rocher, en zoulou), sont attendus en 2021 ou 2022.<\/span><\/p>\n

Un autre, appel\u00e9 RV144, a montr\u00e9 qu\u2019il prot\u00e9geait l\u2019homme du VIH dans une certaine mesure.<\/span> En 2009, une \u00e9tude indiquait qu\u2019il avait r\u00e9duit de 31,2\u2009% le risque d\u2019infection chez 16\u2009000 volontaires<\/span> en Tha\u00eflande.<\/span><\/p>\n

\"\"<\/p>\n

Une avanc\u00e9e d\u00e9cisive\u2009?<\/strong><\/span><\/p>\n

L\u2019\u00e9tude publi\u00e9e samedi rapporte les<\/span> r\u00e9sultats d\u2019un test chez 393 adultes en bonne sant\u00e9, s\u00e9ron\u00e9gatifs, \u00e2g\u00e9s de 18 \u00e0 50\u00a0ans en Afrique de l\u2019Est, Afrique du Sud, Tha\u00eflande et aux \u00c9tats-Unis<\/span>. Certains ont re\u00e7u l\u2019une des combinaisons vaccinales possibles ou un placebo, via quatre injections en 48 semaines. Ces combinaisons \u00e9taient faites de diff\u00e9rents types de virus VIH, rendus suffisamment inoffensifs, avec l\u2019espoir de provoquer une r\u00e9ponse immunitaire. Or celle-ci a \u00e9t\u00e9 \u00ab\u2009robuste\u2009\u00bb<\/strong>, s\u2019est f\u00e9licit\u00e9 le Pr Barouche.<\/span><\/p>\n

Les tests ont montr\u00e9 l\u2019innocuit\u00e9.<\/span> Seuls cinq participants ont fait \u00e9tat d\u2019effets ind\u00e9sirables,<\/span> comme des douleurs abdominales, une diarrh\u00e9e, des vertiges ou des douleurs au dos. Dans une \u00e9tude s\u00e9par\u00e9e, ces m\u00eames vaccins ont offert une<\/span> protection \u00e0 deux tiers des 72 macaques<\/span> auxquels les chercheurs ont ensuite tent\u00e9 d\u2019inoculer le virus.<\/span><\/p>\n

\u00a0\u00a0Avec Ouest-France<\/span><\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

Les r\u00e9sultats d\u2019un vaccin exp\u00e9rimental contre le sida viennent d\u2019\u00eatre pr\u00e9sent\u00e9s par l\u2019\u00e9quipe du virologue Dan Barouch de l\u2019universit\u00e9 d\u2019Harvard (\u00c9tats-Unis). Un test sur des milliers de personnes va \u00eatre lanc\u00e9 en Afrique australe. Des chercheurs ont fait \u00e9tat samedi\u00a0 07 Juillet 2018,d\u2019un progr\u00e8s encourageant, avec un vaccin exp\u00e9rimental qui a provoqu\u00e9 une r\u00e9action immunitaire[…]\n","protected":false},"author":14,"featured_media":3478,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"ngg_post_thumbnail":0,"footnotes":""},"categories":[5],"tags":[],"class_list":["post-3477","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-actualite"],"yoast_head":"\nRecherche et Vih :Un nouveau vaccin prometteur test\u00e9 prochainement - CNLS<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/cnls.sn\/?p=3477\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Recherche et Vih :Un nouveau vaccin prometteur test\u00e9 prochainement - CNLS\" \/>\n<meta property=\"og:description\" content=\"Les r\u00e9sultats d\u2019un vaccin exp\u00e9rimental contre le sida viennent d\u2019\u00eatre pr\u00e9sent\u00e9s par l\u2019\u00e9quipe du virologue Dan Barouch de l\u2019universit\u00e9 d\u2019Harvard (\u00c9tats-Unis). 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