{"id":2690,"date":"2018-04-18T11:35:23","date_gmt":"2018-04-18T11:35:23","guid":{"rendered":"https:\/\/cnls.sn\/?post_type=nos_actualites&p=2690"},"modified":"2018-04-18T11:35:23","modified_gmt":"2018-04-18T11:35:23","slug":"prevention-de-linfection-a-vih-un-implant-pour-se-proteger-contre-le-virus","status":"publish","type":"post","link":"https:\/\/cnls.sn\/?p=2690","title":{"rendered":"Pr\u00e9vention de l\u2019infection \u00e0 Vih : Un implant pour se prot\u00e9ger contre le virus"},"content":{"rendered":"

Des chercheurs canadiens ont con\u00e7u un implant vaginal ayant pour but de prot\u00e9ger les femmes contre une infection par le VIH.<\/em><\/strong><\/span><\/p>\n

\u00a0Des chercheurs de l’Universit\u00e9 de Waterloo, au Canada, ont con\u00e7u un implant ressemblant \u00e0 un st\u00e9rilet \u00a0\u00a0pour prot\u00e9ger les femmes contre une infection par le<\/span> virus du Sida<\/span><\/a>. Les r\u00e9sultats de leurs recherches sont parus dans le<\/span> Journal of Controlled Release<\/a><\/em>.<\/strong><\/span><\/p>\n

Un implant vaginal favorisant l’immunit\u00e9<\/strong><\/p>\n

La science a d\u00e9j\u00e0 montr\u00e9 que le VIH, lors d’un rapport sexuel,<\/span> infecte le corps en d\u00e9clenchant une r\u00e9action inflammatoire et en poussant les lymphocytes T<\/a> <\/strong>vaginaux, des cellules de l’immunit\u00e9, \u00e0 aller combattre le virus.<\/span> Or, lorsque ces cellules ne s’activent pas et ne partent pas attaquer le virus, la personne n’est pas infect\u00e9e et ne transmet pas non plus le VIH \u00e0 une autre personne. On dit alors que les lymphocytes T sont immunis\u00e9s<\/span>. Les chercheurs ont observ\u00e9 ce cas chez des prostitu\u00e9es k\u00e9nyanes qui avaient eu des rapports sexuels avec des clients s\u00e9ropositifs, mais qui n’avaient pas contract\u00e9 la maladie : leurs lymphocytes \u00e9taient naturellement immunis\u00e9s.<\/span><\/p>\n

Les scientifiques canadiens se sont inspir\u00e9s de ces cas et ont<\/span> cherch\u00e9 \u00e0 induire chimiquement cette immunit\u00e9.<\/span> Ils ont alors con\u00e7u un implant vaginal compos\u00e9 d’un tube creux et de deux bras pliables afin qu’il soit maintenu en place.<\/span> Ce dernier lib\u00e8re lentement de l’hydroxychloroquine, absorb\u00e9 ensuite par les parois du vagin. Cette mol\u00e9cule permet d’<\/span>att\u00e9nuer l’activation et l’inflammation des lymphocytes T vaginaux.<\/span> Ce dispositif a \u00e9t\u00e9 test\u00e9 avec succ\u00e8s sur un mod\u00e8le animal.<\/span><\/p>\n

Les recherches continuent<\/strong><\/span><\/p>\n

\u00a0\u00bb Nous savons que<\/span> certains m\u00e9dicaments administr\u00e9s par voie orale ne parviennent jamais au tractus vaginal.<\/span> Cet implant pourrait donc fournir<\/span> un moyen plus fiable d’encourager les lymphocytes T \u00e0 ne pas contracter l’infection et ainsi pr\u00e9venir la transmission de fa\u00e7on plus fiable et moins co\u00fbteuse<\/span> \u00ab\u00a0, a d\u00e9clar\u00e9 dans un communiqu\u00e9 Emmanuel Ho, l’un des auteurs principaux de l’\u00e9tude. \u00ab\u00a0En d\u00e9livrant le m\u00e9dicament exactement o\u00f9 il le faut, nous esp\u00e9rions augmenter les chances d’induire une quiescence immunitaire \u00ab\u00a0.<\/span> Les recherches futures consisteront \u00e0 savoir si ce dispositif peut se suffire \u00e0 lui-m\u00eame ou s’il doit \u00eatre utilis\u00e9 en conjonction avec d’autres strat\u00e9gies de pr\u00e9vention.<\/span><\/p>\n

\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Avec<\/span> The Journal of Controlled\u00a0 Release<\/span><\/p>\n

\u00a0<\/strong><\/p>\n

\n","protected":false},"excerpt":{"rendered":"

Des chercheurs canadiens ont con\u00e7u un implant vaginal ayant pour but de prot\u00e9ger les femmes contre une infection par le VIH. \u00a0Des chercheurs de l’Universit\u00e9 de Waterloo, au Canada, ont con\u00e7u un implant ressemblant \u00e0 un st\u00e9rilet \u00a0\u00a0pour prot\u00e9ger les femmes contre une infection par le virus du Sida. Les r\u00e9sultats de leurs recherches sont[…]\n","protected":false},"author":14,"featured_media":2691,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"ngg_post_thumbnail":0,"footnotes":""},"categories":[5],"tags":[],"class_list":["post-2690","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-actualite"],"yoast_head":"\nPr\u00e9vention de l\u2019infection \u00e0 Vih : Un implant pour se prot\u00e9ger contre le virus - CNLS<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/cnls.sn\/?p=2690\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Pr\u00e9vention de l\u2019infection \u00e0 Vih : Un implant pour se prot\u00e9ger contre le virus - CNLS\" \/>\n<meta property=\"og:description\" content=\"Des chercheurs canadiens ont con\u00e7u un implant vaginal ayant pour but de prot\u00e9ger les femmes contre une infection par le VIH. \u00a0Des chercheurs de l’Universit\u00e9 de Waterloo, au Canada, ont con\u00e7u un implant ressemblant \u00e0 un st\u00e9rilet \u00a0\u00a0pour prot\u00e9ger les femmes contre une infection par le virus du Sida. 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